Process for recycling solid supports for cultivation of anchorage-dependent cells
US8080419B2 · kind B2 · utility
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28Claims
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Key dates
| Filing date | Nov 26, 2004 |
| Grant date | Dec 20, 2011 |
| Priority date | — |
| Expiry date | Jul 14, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to methods for use in industrial production of proteins. Specifically, the present invention provides a method of recycling solid supports for cultivation of anchorage-dependent cells such as, e.g., microcarriers and Fibra-Cel® disks. Solid supports recycled by a method of the present invention allow obtaining a protein productivity level comparable to the productivity level obtained with non-recycled solid support. The method comprises the steps of rinsing with water, rinsing with a sodium hydroxide solution and second rinsing step with water.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.