Combinations comprising a CDK inhibitor and a growth factor antibody or anti-mitotic
US8084027B2 · kind B2 · utility
0Cited by
2References
25Claims
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Assignee
Inventors
Key dates
| Filing date | Feb 2, 2007 |
| Grant date | Dec 27, 2011 |
| Priority date | — |
| Expiry date | Aug 26, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a combination comprising a compound A of formula (I) as set forth in the specification or a pharmaceutically acceptable salt thereof, and an antibody inhibiting a growth factor or its receptor and/or an antimitotic agent or a derivative or prodrug thereof, useful in the treatment of tumors. The chemical name of compound A is 8-[4-(4-methyl-piperazin-1-yl)-phenylamino]-1,4,4-trimethyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid methylamide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.