Biodegradable linkers for molecular therapies
US8084435B2 · kind B2 · utility
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1Claims
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Key dates
| Filing date | May 3, 2007 |
| Grant date | Dec 27, 2011 |
| Priority date | — |
| Expiry date | Dec 13, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and a composition for delivery of a biomaterial to an animal cell or a tissue, the composition includes (a) a biomaterial; (b) a biodegradable cross-linker portion having a hydrolyzable bond, wherein the biodegradable cross-linker portion is covalently bound to the biomaterial; and (c) a substrate, wherein the substrate is covalently bound to the biodegradable cross-linker portion, provided that the biodegradable cross-linker is adapted to hydrolyze by breaking the hydrolyzable bond and thereby release and deliver the biomaterial. A process of making the composition is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.