Patent · US Active

3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof

US8084462B2 · kind B2 · utility

10Cited by

22References

2Claims

0Family size

Assignee

Targacept, Inc. · US

Inventors

Anatoly Mazurov · Greensboro, US
Jozef Klucik · Marietta, US
Lan Miao · Advance, US
Angela S. Seamans · Jamestown, US
Teresa Phillips · Durham, US
Jeffrey Daniel Schmitt · Winston-Salem, US
Craig Harrison Miller · Winston-Salem, US

Key dates

Filing date	Jun 4, 2010
Grant date	Dec 27, 2011
Priority date	—
Expiry date	Jun 4, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the pharmaceutical compositions incorporating compounds capable of affecting nicotinic acetylcholinergic receptors (nAChRs), for example, as modulators of specific nicotinic receptor subtypes (specifically, the α7 nAChR subtype). The present invention also relates to methods for treating a wide variety of conditions and disorders, particularly those associated with dysfunction of the central and autonomic nervous systems.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.