Processes for the preparation of 4-oxo-octahydro-indole-1-carbocyclic acid methyl ester and derivatives thereof

US8084487B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Ernst Kuesters · Sankt Goarshausen, DE
• Murat Acemoglu · Basel, CH
• Philipp Lustenberger · Warthausen, DE
• Gottfried Sedelmeier · Schallstadt, DE
• Beat Schmitz · Allschwil, CH
• Gerhard Penn · Oberwil, CH

Key dates

• Filing date: Aug 10, 2009
• Grant date: Dec 27, 2011
• Expiry date: Aug 10, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for the production of carbamic acid (2-chloroethyl)(3-oxocyclohexyl)-alkyl ester enantiomers and of 1-carbalkoxy-4-ketoperhydroindole enantiomers.