Labelled nucleotides
US8084590B2 · kind B2 · utility
32Cited by
14References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 21, 2010 |
| Grant date | Dec 27, 2011 |
| Priority date | — |
| Expiry date | Jun 21, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterised in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a C1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl). T is hydrogen or a C1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.