Short interfering ribonucleic acid (siRNA) with improved pharmacological properties
US8084600B2 · kind B2 · utility
33Cited by
19References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 2, 2007 |
| Grant date | Dec 27, 2011 |
| Priority date | — |
| Expiry date | May 29, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.