Patent · US Active

Pharmaceutical compositions comprising fesoterodine

US8088398B2 · kind B2 · utility

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16Claims

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Assignee

UCB Pharma GMBH · DE

Inventors

Hans-Jurgen Mika · Bonn, DE
Christoph Arth · Düsseldorf, DE
Michael Komenda
Fatima Bicane · Sankt Goarshausen, DE

Key dates

Filing date	Dec 23, 2008
Grant date	Jan 3, 2012
Priority date	—
Expiry date	Oct 3, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present application relates to a pharmaceutical granulate comprising Fesoterodine or a pharmaceutically acceptable salt or solvate thereof and a pharmaceutically acceptable stabilizer, which can be selected from the group consisting of sorbitol, xylitol, polydextrose, isomalt, dextrose, and combinations thereof, and is preferably a sugar alcohol selected from the group consisting of xylitol and sorbitol. The granulate is suitable for incorporation into pharmaceutical compositions comprising a gel matrix formed by at least one type of hydroxypropyl methylcellulose into which the Fesoterodine is embedded and, optionally, further excipients. In certain embodiments, the granulate is formed by a process of wet granulation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.