Method of producing a body fluid sample depleted of anti-MHC antibodies
US8088586B2 · kind B2 · utility
0Cited by
15References
10Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 22, 2003 |
| Grant date | Jan 3, 2012 |
| Priority date | — |
| Expiry date | Jul 22, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/25375
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides a method of depleting anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and removing at least the recombinant MHC molecules to which antibodies to said recombinant MHC molecules contained within the sample have bound. This method allows the depletion of one or more specific MHC particularly HLA allele antibodies from a sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.