CTLA-4 protein variants
US8088736B2 · kind B2 · utility
6Cited by
1References
19Claims
0Family size
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Key dates
| Filing date | Oct 22, 2007 |
| Grant date | Jan 3, 2012 |
| Priority date | — |
| Expiry date | Jan 13, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Protein variants of CTLA-4, which show increased activity compared to wild-type in a cell assay and which exhibit increased stability. Such variants are useful for treatment of disorders whereby attenuation of the T cell response would be beneficial.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.