Benzoxazole carboxamide inhibitors of poly(ADP-ribose)polymerase (PARP)
US8088760B2 · kind B2 · utility
23Cited by
5References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 16, 2009 |
| Grant date | Jan 3, 2012 |
| Priority date | — |
| Expiry date | Aug 21, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound having the structure set forth in Formula (I) or Formula (II):wherein the variables Y, R1, R2, R3, and R4 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.