Patent · US Active

Compound useful for the treatment of degenerative and inflammatory diseases

US8088764B2 · kind B2 · utility

17Cited by

0References

15Claims

0Family size

Assignee

Galapagos NV · BE

Inventors

Christel Jeanne Marie Menet · Mechelen, BE
Koen Kurt Smits · Mechelen, BE

Key dates

Filing date	Jun 25, 2010
Grant date	Jan 3, 2012
Priority date	—
Expiry date	Jun 25, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A novel compound able to inhibit JAK is disclosed, that comprises a compound according to Formula I:or a pharmaceutically acceptable salt thereof. The compound may be prepared as a pharmaceutical composition, and may be used for the treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.