Patent · US Active

Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor

US8088799B2 · kind B2 · utility

0Cited by

6References

4Claims

0Family size

Assignee

Sanofi-Aventis Deutschland GMBH · DE

Inventors

Wolfgang Linz · Mainz, DE
Ursula Schindler · Bad Soden, DE

Key dates

Filing date	Aug 4, 2004
Grant date	Jan 3, 2012
Priority date	—
Expiry date	Jun 27, 2027

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/403
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention is directed to a pharmaceutical composition comprising the sodium-hydrogen exchanger (NHE) inhibitor cariporide and an angiotensin converting enzyme (ACE) inhibitor which exhibits unexpectedly efficacious properties for preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life, and to methods of preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life comprising administering pharmaceutically effective amounts of the sodium-hydrogen exchange inhibitor cariporide and an ACE inhibitor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.