Generation and profiling of fully human gold-derived therapeutic antibodies specific for human CD38

US8088896B2 · kind B2 · utility

Assignee

• MORPHOSYS AG · DE

Inventors

• Michael Tesar · Heidelberg, DE
• Ute Jäger · Höchst im Odenwald, DE

Key dates

• Filing date: Oct 12, 2006
• Grant date: Jan 3, 2012
• Expiry date: Jan 15, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/732
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides novel antibodies and functional fragments thereof specific for CD38, and methods for using the same. These antibodies as well as the novel methods for using those antibodies can be used to treat, for example, hematological malignancies such as multiple myeloma.