Heteroaryl-carboxylic acid (sulfamoyl alkyl) amide-derivatives as factor Xa inhibitors

US8088925B2 · kind B2 · utility

Assignee

• Sanofi-Aventis · FR

Inventors

• Michael Wagner · Frankfurt am Main, DE
• Matthias Urmann · Eschborn, DE
• Volkmar Wehner · Bischofsheim a.d.Rhön, DE
• Martin Lorenz · Frankfurt am Main, DE
• Armin Bauer · Pocking, DE
• Marc Nazare · Idstein, DE
• Hans Matter · Langenselbold, DE

Key dates

• Filing date: Nov 15, 2007
• Grant date: Jan 3, 2012
• Expiry date: Feb 14, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D419/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of the formula I,which exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses.