Alpha-substituted α,β-unsaturated E- or Z-aldehydes, use thereof, and processes for their preparation α,β

US8088955B2 · kind B2 · utility

Assignee

• DSM Fine Chemicals Austria NFG GmbH & Co KG · AT

Inventors

• Gerhard Steinbauer · Ansfelden, AT
• Martina Kotthaus · Linz, AT
• Klaus Edegger · Linz, AT
• Stefaan Marie Andre De Wildeman · Maasmechelen, BE
• Henricus Martinus Maria Gerardus Straatman · Horst, NL
• Anna M. C. F. Castelijns · Geleen, NL
• Andreas Hendrikus Maria De Vries · Echt, NL

Key dates

• Filing date: Jul 11, 2008
• Grant date: Jan 3, 2012
• Expiry date: Jul 11, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P7/24
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to novel alpha-substituted α,β-unsaturated E- or Z-aldehydes, or isomer mixture thereof, of the formula (I) in which R1 and R2 may be identical or different and are each H or a hydrocarbon, in which the hydrocarbon may have one or more heteroatoms and R3 and R4 may be identical or different and are each a hydrocarbon, in which the hydrocarbon may have one or more heteroatoms, and R5 may be identical or different and is H or a hydrocarbon, in which the hydrocarbon may have one or more heteroatoms, to the use thereof, and to processes for their preparation. The invention further relates to the preparation of further intermediates for pharmaceuticals and to the preparation of the pharmaceuticals.