Process for the production of substituted bromobenzenes
US8088960B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Oct 8, 2007 |
| Grant date | Jan 3, 2012 |
| Priority date | — |
| Expiry date | Oct 8, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C25/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process for the production of compounds of formula (I) wherein X is fluoro, chloro, bromo or iodo and n is 1, 2, 3 or 4, which process comprises reacting a compound of formula (II) wherein the substituents are as defined for formula (I), with inorganic nitrite in an acidic aqueous medium in the presence of bromide and a copper catalyst and wherein the process is carried out as a one-pot reaction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.