Bilirubin oxidase mutant having thermal stability
US8093029B2 · kind B2 · utility
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Key dates
| Filing date | May 19, 2009 |
| Grant date | Jan 10, 2012 |
| Priority date | — |
| Expiry date | Jan 13, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y103/03005
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A heat-resistant bilirubin oxidase mutant is disclosed. The bilirubin oxidase mutant is obtained by deletion, replacement, addition or insertion of at least one amino acid residue of a wild type amino sequence of SEQ. ID. No. 1 of a bilirubin oxidase derived from an imperfect filamentous fungus, Myrothecium verrucaria. A biocathode including a thermo stable bilirubin oxidase mutant immobilized thereon, and its use in a biofuel cell is disclosed.
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