Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs as HSP90-inhibitors
US8093229B2 · kind B2 · utility
2Cited by
50References
20Claims
0Family size
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Key dates
| Filing date | May 22, 2009 |
| Grant date | Jan 10, 2012 |
| Priority date | — |
| Expiry date | Oct 24, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Alkynyl pyrrolo [2,3-d] pyrimidines of Formula I are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders. Methods of synthesis and use of such compounds are also described and claimed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.