Patent · US Active

O-linked pyrimidin-4-amine-based compounds, compositions comprising them, and methods of their use to treat cancer

US8093246B2 · kind B2 · utility

2Cited by

8References

18Claims

0Family size

Assignee

LEXICON PHARMACEUTICALS, INC. · US

Inventors

David J. Augeri · Princeton, US
Marianne Carlsen · Yardley, US
Kenneth G. Carson · Princeton, US
Qinghong Fu · Plainsboro, US
Jason Healy · Monmouth Junction, US
Alexander Heim-Riether · Ingelheim am Rhein, DE
Theodore C. Jessop · Lawrenceville, US
Philip E. Keyes · Flemington, US
Min-Jui Richard Shen · Boyds, US
James E. Tarver · Levittown, US
Jerry Andrew Taylor · Trenton, US
Xiaolian Xu · Princeton, US

Key dates

Filing date	Dec 12, 2007
Grant date	Jan 10, 2012
Priority date	—
Expiry date	Sep 8, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D409/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

O-linked pyrimidin-4-amine-based compounds, pharmaceutical compositions comprising them, and methods of their use are described. Particular compounds of the invention are of formula I:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.