Heteroaryl sulfonamides and CCR2
US8093247B2 · kind B2 · utility
15Cited by
8References
15Claims
0Family size
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Key dates
| Filing date | Oct 20, 2009 |
| Grant date | Jan 10, 2012 |
| Priority date | — |
| Expiry date | Oct 20, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.