Metallo-β-lactamase inhibitors
US8093294B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Aug 10, 2007 |
| Grant date | Jan 10, 2012 |
| Priority date | — |
| Expiry date | Dec 7, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new metallo-β-lactamase inhibitor which acts as a medicament for inhibiting the inactivation of β-lactam antibiotics and recovering anti-bacterial activities is disclosed. The maleic acid derivatives having the general formula (I) have metallo-β-lactamase inhibiting activities. It is possible to recover the anti-bacterial activities of β-lactam antibiotics against metallo-β-lactamase producing bacteria by combining the compound of the general formula (I) with β-lactam antibiotics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.