Interference control panel for evaluation of analytical assays for samples derived from blood
US8097461B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 15, 2007 |
| Grant date | Jan 17, 2012 |
| Priority date | — |
| Expiry date | Dec 14, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/145555
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to quality control of analytical assays, particularly NAT assays of blood samples containing nucleic acids. A control panel containing quantified amounts of substances known to interfere with an analytical assay is used and compared with a reference sample in the analytical assay. A comparison of the assay results interference panel validates the assay and can serve as a periodic quality control check for the analytical assay as well as related methods and protocols. The use of the control panel of the invention can also determine whether interfering substances are present and establish under what conditions the analytical assay reliable.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.