Iminosugar compounds with antiflavirus activity
US8097728B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 30, 2008 |
| Grant date | Jan 17, 2012 |
| Priority date | — |
| Expiry date | Sep 19, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An anti-viral compounds effective against viruses belonging to the Flaviviridae family, wherein the anti-viral compounds are 1,5-dideoxy-1,5-imino-D-glucitol derivative compounds having the general formula (I)wherein R2, R3, R4 and R5 are the same or different and are selected from the group consisting of hydrogen, acyl, benzyl, alkyl, aryl, sulfonyl, phosphonyl, silyl, R6 is at least one of alkyl or branched alkyl, heteroalkyl or aryl, R6′ is a bridging group selected from at least one of bicycle[2.2.1]heptyl, bicycle[3.2.1]octyl, oxa analogs, admonyl and cubyl, n′=2-10, n″=1-10, enantiomers and stereoisomers of said compounds and physiologically acceptable salts or solvates of said compounds, enantiomer or stereoisomer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.