Patent · US Active

Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof

US8097729B2 · kind B2 · utility

0Cited by

2References

16Claims

0Family size

Assignee

Glenmark Generics Limited · IN

Inventors

Mangesh Shivram Sawant · Mumbai, IN
Maloyesh Mathuresh Biswas · Jamkhed, IN
Mubeen Ahmed Khan · Navi Mumbai, IN
Sukumar Sinha · Mumbai, IN
Nitin Sharad Chandra Pradhan · Thane, IN

Key dates

Filing date	Sep 18, 2006
Grant date	Jan 17, 2012
Priority date	—
Expiry date	Jan 8, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P9/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Processes for the purification of lercanidipine hydrochloride are provided which uses a binary system of an alcohol-containing solvent such as methanol and an aliphatic ester-containing solvent such as isopropyl acetate. Processes for the preparation of substantially amorphous lercanidipine hydrochloride are also provided. Also provided is lercanidipine hydrochloride substantially in polymorph form V.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.