Use of immunogens to treat or prevent, in malignant tumors, the immune or vascular disorders induced by extracellular factors
US8101165B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 13, 2007 |
| Grant date | Jan 24, 2012 |
| Priority date | — |
| Expiry date | Feb 2, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/6081
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns vaccines comprising as an active principle an immunogen which is a cytokinetic factor or a cell regulating factor particularly transcriptional or another type of factor with immunosuppressive/apoptotic/angiogenic properties abnormally released in the extracellular (stromal) environment by cancer or stromal cells of malignant tumors, and a pharmaceutically acceptable carrier for inducing a systemic or mucosal immune response with secretory formation of class IgC or IgA neutralizing antibodies directed against the native factor, or which is derived from such a factor and the use of said immunogen to obtain a medicine for use as anticancer drug.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.