Diagnose device for measuring the ratio of proteins with similar structure
US8101369B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 23, 2006 |
| Grant date | Jan 24, 2012 |
| Priority date | — |
| Expiry date | Jul 7, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/76
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a diagnostic device for measuring the ratio of similar structural proteins among the proteins secreted in a liquid test sample taken from diagnosis subject. In further detail, the test device according to the present invention comprises detection marker-antibody conjugate recognizing the same site on two or more similar structural proteins and a detection zone in which antibody specifically recognizes each of said proteins via formation of sandwich type complex, wherein said antibodies form a set, and the present Invention relates to a diagnostic device for early diagnosis of polycystic ovary syndrome, abnormal pregnancy, prostatic carcinoma etc. based on determination of the ratio of follicle stimulating hormone and luteinizing hormone in case of polycystic ovary syndrome, the ratio between hCG isomers in case of abnormal pregnancy, and the ratio of prostate-specific antigens (PSA) in case of prostatic carcinoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.