β-galactosidase donor fragments
US8101373B2 · kind B2 · utility
7Cited by
14References
14Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 10, 2008 |
| Grant date | Jan 24, 2012 |
| Priority date | — |
| Expiry date | Dec 26, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Truncated fragments of the small fragment of β-galactosidase are provided that have low affinity for the large fragment of β-galactosidase and provide for robust signals when two fusion proteins are complexed due to the binding of the proteins to which the β-galactosidase fragments are fused. The truncated fragments do not interfere with the complexing of the two proteins and allow for the two proteins to function and be responsive to candidate compounds that affect complex formation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.