Methods for regulating osteoclast differentiation and bone resorption using LRRc17
US8101564B2 · kind B2 · utility
9Cited by
9References
9Claims
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Key dates
| Filing date | May 3, 2007 |
| Grant date | Jan 24, 2012 |
| Priority date | — |
| Expiry date | May 3, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a purified, negative regulator of osteoclast differentiation and bone resorption, specifically LRRc17. Further provided are methods and compositions for treating degenerative bone disorders, and treatments and prophylactic approaches for regulating bone resorption, and for decreasing or inhibiting the excessive bone loss associated with abnormal or excessive generation of or activity of osteoclasts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.