Fumaric acid derivatives and ophthalmic lenses using the same
US8101701B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 22, 2007 |
| Grant date | Jan 24, 2012 |
| Priority date | — |
| Expiry date | Jun 11, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/0838
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Fumaric acid derivatives and ophthalmic lenses using them are disclosed. More specifically, a fumaric acid derivative having a hydrophilic group and a silicon-containing alkyl group within a molecule, and contact lenses or intraocular lenses using the same are disclosed. The fumaric acid derivatives of the present invention provide, on one hand, superior oxygen permeability by having a silicon-containing alkyl group within the molecular structure, and on the other hand, improved compatibility with other hydrophilic monomers by having a hydrophilic group within the same molecule. When ophthalmic lenses obtained by polymerizing monomer compositions containing the fumaric acid derivative are constructed as, for example, water content lenses, lenses with high oxygen permeability independent from the water content may be obtained, wherein the fumaric acid derivatives is superior in compatibility with the hydrophilic monomer used in combination and allows the combination in various mixing ratios.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.