Patent · US Active

Polynucleotides and polypeptide of human KV1.3, compositions comprising same and methods of using same

US8101736B2 · kind B2 · utility

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Key dates

Filing dateDec 12, 2006
Grant dateJan 24, 2012
Priority date
Expiry dateFeb 5, 2029

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An isolated polypeptide comprising, contiguously, a first amino acid sequence being at least 90% homologous to amino acid coordinates 1-398 of SEQ ID NO: 2, a tryptophan residue and a second amino acid sequence being at least 90% homologous to amino acid coordinates 400-523 of SEQ ID NO:2. Also provided are polynucleotide sequences encoding this polypeptide and uses of same in the treatment of medical conditions associated with ion channel insufficiency.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.