Patent · US Active

Process for preparing acyclic HCV protease inhibitors

US8101765B2 · kind B2 · utility

11Cited by

6References

6Claims

0Family size

Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Carl Alan Busacca · Poughkeepsie, US
Rogelio P. Frutos · Sandy Hook, US
Nizar Haddad · Danbury, US
Suresh R. Kapadia · Danbury, US
Jon Lorenz · New Milford, US
Anjan Saha · Hamden, US
Chris Hugh Senanayake · Brookfield, US
Xudong Wei · West Greenwich, US

Key dates

Filing date	Jan 16, 2009
Grant date	Jan 24, 2012
Priority date	—
Expiry date	Apr 4, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection:The disclosed processes use SNAr-type coupling reactions between peptidic compounds having a hydroxyproline moiety of the following formula:and halogenated or sulfonated bromoquinoline compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.