Treatment of neoplasms with viruses
US8105578B2 · kind B2 · utility
31Cited by
21References
63Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 29, 2007 |
| Grant date | Jan 31, 2012 |
| Priority date | — |
| Expiry date | Jun 28, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/36132
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.