Methods of antagonizing signal transduction in dorsal root ganglion cells
US8105591B2 · kind B2 · utility
38Cited by
19References
5Claims
0Family size
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Key dates
| Filing date | Mar 30, 2011 |
| Grant date | Jan 31, 2012 |
| Priority date | — |
| Expiry date | Mar 30, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Use of antagonists to IL-31Ra and OSMRb are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such antagonists include soluble receptors, antibodies and fragments, derivative, or variants thereof. Symptoms such as pain, tingle, sensitization, tickle associated with neuropathies are ameliorated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.