Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia
US8105607B2 · kind B2 · utility
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13References
7Claims
0Family size
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Key dates
| Filing date | Apr 5, 2005 |
| Grant date | Jan 31, 2012 |
| Priority date | — |
| Expiry date | Nov 25, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention features the use of PorB polypeptide as a therapeutic agent. In specific embodiment the invention features a chlamydial vaccine based on a PorB polypeptide, as well as methods for induction of a protective immune response against infection by Chlamydia and Chlamydiophila. The invention further features methods for identifying agents that affect PorB function (such as in transport of α-ketoglutarate and which are effective as anti-chlamydial chemotherapeutic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.