Device and method of detecting mutations and polymorphisms in DNA
US8105780B2 · kind B2 · utility
71Cited by
11References
42Claims
0Family size
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Key dates
| Filing date | Sep 22, 2004 |
| Grant date | Jan 31, 2012 |
| Priority date | — |
| Expiry date | Mar 27, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
There is provided a resonator sensor useful for detecting polymorphisms and mutations in DNA. The resonator sensor has a capture molecule immobilised on its surface, the capture molecule being either a probe DNA containing a reference sequence, or a mismatch binding molecule, and being capable of forming a probe DNA/target DNA/mismatch binding molecule complex on the surface of the resonator. A method for detecting mutations in a target DNA, including single nucleotide polymorphisms, is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.