Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity
US8106043B2 · kind B2 · utility
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25Claims
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Key dates
| Filing date | Jul 6, 2009 |
| Grant date | Jan 31, 2012 |
| Priority date | — |
| Expiry date | Sep 25, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention features benzothiazines that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms, and that have the formula:The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.