Spiro-oxindole compounds and their uses as therapeutic agents
US8106087B2 · kind B2 · utility
17Cited by
41References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 30, 2009 |
| Grant date | Jan 31, 2012 |
| Priority date | — |
| Expiry date | Dec 30, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to spiro-oxindole compounds of formula (I):wherein k, j, Q, R1, R2a, R2b, R2c, R2d, R3a, R3b, R3c, and R3d are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of preparing and using the compounds are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.