Patent · US Active

Combination of phenylcarboxamides with blockers of the IKr channel and their use for the treatment of atrial arrhythmias

US8106099B2 · kind B2 · utility

6Cited by

1References

6Claims

0Family size

Assignee

Sanofi-Aventis Deutschland GMBH · DE

Inventors

Joachim Brendel · Bad Vilbel, DE
Klaus Wirth · Frankfurt am Main, DE
Heinz GOEGELEIN · Frankfurt, DE
Maurits Allessie · Eijsden, NL
Yuri Blaauw · Eijsden, NL

Key dates

Filing date	Mar 9, 2004
Grant date	Jan 31, 2012
Priority date	—
Expiry date	Mar 7, 2027

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/44
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to the combination of one or more IKr channel blockers and of one or more Kv1.5 blockers, in particular phenyl-carboxamides of the formula Ia or Ibor pharmaceutically tolerable salts thereof, and the use of the combination for the treatment of atrial arrhythmias.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.