Process for the preparation of (2R,3S)-3-phenylisoserine methyl ester acetate salt
US8106231B2 · kind B2 · utility
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Key dates
| Filing date | Feb 11, 2008 |
| Grant date | Jan 31, 2012 |
| Priority date | — |
| Expiry date | Feb 11, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C233/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the enantioselective preparation of (2R,3S)-3-phenylisoserine methyl ester acetate salt of formula (I) which is an useful building block for the synthesis of taxane derivatives. The process involves the resolution of racemic threo-phenylisoserine amide and its conversion into (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.