Degradation and detection of TSE infectivity
US8110391B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Oct 11, 2007 |
| Grant date | Feb 7, 2012 |
| Priority date | — |
| Expiry date | Jul 22, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2828
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A transmissible spongiform encephalopathy (TSE) agent is inactivated by exposing the TSE agent to a thermostable proteolytic enzyme at elevated temperature and at acid or alkaline pH. Following this step, or separately, presence of TSE infectivity is detected by detection of dimers of prion protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.