Method to measure serum biomarkers for the diagnosis of liver fibrosis
US8110409B2 · kind B2 · utility
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17References
12Claims
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Key dates
| Filing date | Sep 12, 2007 |
| Grant date | Feb 7, 2012 |
| Priority date | — |
| Expiry date | Dec 13, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/805
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention discloses using SPR technology to simultaneously and quantitatively measure the concentrations of different liver fibrosis-associated serum biomarkers in a serum sample, which can be used for the diagnosis of liver fibrosis. It also discloses an efficient formula to make a mixed SAM that can greatly enhance the immobilization ability of the metal surface in SPR based techniques, which is good for the immobilization of relevant antibodies used for the detection of liver fibrosis-associated serum biomarkers for the diagnosis of liver fibrosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.