Compounds

US8110575B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Dirk Gottschling · Mittelbiberach, DE
• Georg Dahmann · Biberach an der Riß, DE
• Henri Doods · Warthausen, DE
• Annekatrin Heimann · Biberach, DE
• Stephan Georg Mueller · Warthausen, DE
• Klaus Rudolf · Warthausen, DE
• Gerhard Schaenzle · Biberach, DE
• Dirk Stenkamp · Biberach, DE

Key dates

• Filing date: Nov 21, 2008
• Grant date: Feb 7, 2012
• Expiry date: Nov 21, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to new CGRP-antagonists of general formula Iwherein U, V, X, Y, R1, R2, R3 and R4 are defined as in the description, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates, the mixtures thereof and the salts thereof and the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, their use and processes for preparing them.