Promoter engineering and genetic control
US8110672B2 · kind B2 · utility
3Cited by
10References
52Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 26, 2006 |
| Grant date | Feb 7, 2012 |
| Priority date | — |
| Expiry date | Jun 9, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/1086
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to expression cassettes libraries of expression vectors comprising the same, wherein each vector comprises at least one gene of interest and a promoter operatively linked thereto wherein each promoter comprises a nucleic acid, whose sequence is randomly mutated with respect to that of another in the library and cells comprising the same. Methods utilizing either the libraries or cells of this invention, in optimizing gene expression, protein expression, or optimized gene or protein delivery are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.