Radiolabeled compounds and compositions, their precursors and methods for their production
US8114381B2 · kind B2 · utility
5Cited by
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22Claims
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Key dates
| Filing date | Feb 14, 2005 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Jun 10, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/05
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Positron emitting compounds and methods of their production are provided. The compounds have the formula: (F)m G (R)n wherein each R is a group comprising at least one carbon, nitrogen, phosphorus or sulfur atom and G is joined to R through said carbon, nitrogen, phosphorus or sulfur atom; G is silicon or boron; m is 2 to 5 and n is 1 to 3 with m+n=3 to 6 when G is silicon; m is 1 to 3 and n is 1 to 3 with m+n=3 to 4 when G is boron; and wherein the compound further comprises one or more counterions when the above formula is charged; and wherein at least one F is 18F.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.