Compositions and methods for treatment of cervical cancer
US8114414B2 · kind B2 · utility
22Cited by
28References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 8, 2007 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Jan 9, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods of treating, protecting against, and inducing an immune response against cervical cancer, comprising the step of administering to a subject a recombinant Listeria strain, comprising a fusion peptide that comprises an LLO fragment and an E7 and/or E6 antigen. The present invention also provides methods for inducing an anti-E7 response in a human subject and treating HPV-mediated diseases, disorders, and symptoms comprising administration of the recombinant Listeria strain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.