Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8114429B2 · kind B2 · utility
34Cited by
61References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 17, 2010 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Mar 17, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/109
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which comprises poly(HEMA) complexed with iodine and has a substantially water-insoluble therapeutic agent dispersed therein. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.