Biomolecular coating for implants
US8114431B2 · kind B2 · utility
5Cited by
1References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 19, 2007 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Jul 29, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/412
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are provided. The substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are shown to have greater tissue formation on the surface relative to controls, in particular greater bone formation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.