Highly conserved genes and their use to generate probes and primers for detection of microorganisms
US8114601B2 · kind B2 · utility
9Cited by
30References
11Claims
0Family size
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Key dates
| Filing date | Sep 27, 2005 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Aug 23, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Four highly conserved genes, encoding translation elongation factor Tu, translation elongation factor G, the catalytic subunit of proton-translocating ATPase and the RecA recombinase, are used to generate species-specific, genus-specific, family-specific, group-specific and universal nucleic acid probes and amplification primers to rapidly detect and identify algal, archaeal, bacterial, fungal and parasitical pathogens from clinical specimens for diagnosis. The detection of associated antimicrobial agents resistance and toxin genes are also under the scope of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.