Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays
US8114618B2 · kind B2 · utility
5Cited by
12References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 5, 2011 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Apr 5, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/107497
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic antibody:antigen complex, soluble antigen and soluble therapeutic antibody, wherein a patient has undergone at least one course of immunotherapy. Yet further, levels of therapeutic antibody:antigen complexes, soluble antigens or soluble therapeutic antibodies may be measured and used to stage or monitor a hyperproliferative disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.